Andre is about an animal who adopts a needy family. Young Toni Whitney (Tina Marjorino) is unpopular at school. Her father Steve (Keith Carradine) is not really suited to his job as harbormaster in Rockport, Maine. Then one day he rescues a seal pup whose mother has been killed in a net. As Andre the seal grows up he becomes the friend Toni desperately needs and a key to Steve's finding his vocation. This film, based on a true story, demonstrates the incredible bond that some animals can feel toward human families.