One of the unspoken realizations of many people around the globe these days is that we are now paying the price for humanity's unrepentant pride and reckless domination of the good Earth. Just look at what's been happening — all kinds of so-called natural disasters, dramatic changes in weather patterns, and the extinction of whole species of animals. We've been messing with Mother Nature, and she is not happy.

Deep Blue Sea makes a very scary film out of this premise. It is set on a marine biology base in the ocean off the Mexico coast where a team of scientists and animal experts are conducting experiments on sharks in order to find a cure for Alzheimer's disease. Russell Franklin (Samuel L. Jackson), the head of a pharmaceutical company and chief investor in this project, is being shown around the place by geneticist Susan McAlester (Saffron Burrows), a woman whose obsession with the work separates her from her colleagues. Unbeknownst to the others at the lab, she and Dr. Jim Whitlock (Stellan Skarsgard) have broken an international ethical code by genetically altering the brains of three voracious sharks in order to grow more cells for their tests. The already dangerous fish have gotten much larger and smarter. Soon the tables are turned as the unfortunate folk on the floating lab find themselves at the mercy of these predators who want revenge and their freedom.

Renny Hardin directs this suspenseful thriller whose most endearing character is Dudley (LL Cool J), a chef who cooks up some clever escapes and comes up with an unusual foxhole prayer. At one point, his crucifix actually becomes a key that saves him from certain death.