Lorenzo's Oil tells the true story of an Italian economist and an Irish-American linguist who fashioned a miracle to save the life of their son Lorenzo.

Screenplay writers George Miller and Nick Enright give poignancy to this medical detective story by emphasizing the spiritual resourcefulness of these parents.

Susan Sarandon as the mother invests ferocious energy in caring for her son's body and soul. Nick Nolte as the father embarks on an intensive research project on his own, even sponsoring an international conference, when he learns that the medical establishment has not given much attention to the "orphan disease" affecting Lorenzo.

Miracles, they prove, can be made by anyone and all of us. Love, in the end, is the best life support system.